Diagnosis and Treatment of Hypopituitarism

Evaluation of an Infant with Cholestasis and Congenital Hypopituitarism

We are reporting an infant with persistent abnormal liver function, neonatal jaundice, and intermittent hypoglycemia. Evaluation confirmed congenital hypopituitarism, in the absence of congenital anomalies and midline defect. His jaundice and abnormal liver function improved after treatment with Levothyroxine and hydrocortisone.

Hypopituitarism in adult patients with non-pituitary brain cancer following radiation therapy

Introduction:  The purpose and our novelty of the current study were to evaluate the HPA function in adult survivors of primary non-pituitary brain tumors and its association with treatment-related factors such as received dose to the organs at risk, age at irradiation, surgery, and adjuvant chemotherapy in patients treated with RT for brain tumors. Moreover, it aimed to achie...

An Update on Subclinical Hypopituitarism

Subclinical deficiency of pituitary hormones represents an intermediate situation among normal pituitary secretion and overt hypopituitarism. Clinical hypopituitarism is associated with impaired morbidity and mortality, but there are not many studies on these topics in the subclinical setting. Moreover, clinical manifestations and diagnosis criteria are not well defined, so this entity is proba...

Hypopituitarism — Symptoms, Diagnosis and Treatment

Hypopituitarism — Symptoms, Diagnosis and Treatment

Mortality in Hypopituitarism Causes Clinical Features Diagnosis and Endocrine Assessment Treatment of Hypopituitarism Strategies to Prevent Hypopituitarism

Hypopituitarism is the deficiency of one or more pituitary hormones. It is relatively rare, with a prevalence of 45 per million and an annual incidence of about 4 per 100,000.1 It is, however, seen commonly in endocrine practice and, importantly, is associated with increased morbidity and mortality. Clinical manifestations are influenced by the etiology, severity, and rate of onset of pituitary...